Nizhne-Pokrovskaya Street is one of the oldest streets in Polotsk. Historical sources confirm its existence already in the second half of the 11th — beginning of the 12th century. From the 13th century the street was densely populated, served as one of the main streets in the city, it was crossed by the Dvina River to the city markets, churches, synagogues, Catholic and Orthodox monasteries were located on it, the richest and most influential citizens lived there.
The first known name of this street was Velikaya Street. In the last quarter of the 18th century (in connection with the construction of St. Pokrovskaya Church) it was renamed into Nizhne-Pokrovskaya Street, in 1919 — into Lenin Street, and in 2008 the street again returned the name Nizhne-Pokrovskaya. It received its current direction in accordance with the classicist plan of Polotsk developed and approved in the late 18th century, which gave the layout of the historical center of the city the features of regularity.